The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

Domain V of the 23S/25S/28S rRNA of the large ribosomal subunit constitutes the active center for the protein folding activity of the ribosome (PFAR). Using in vitro transcribed domain V rRNAs from Escherichia coli and Saccharomyces cerevisiae as the folding modulators and human carbonic anhydrase a...

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Main Authors: Pang, Yanhong, Kurella, Sriram, Voisset, Cécile, Samanta, Dibyendu, Banerjee, Debapriya, Schabe, Ariane, Das Gupta, Chanchal, Galons, Hervé, Blondel, Marc, Sanyal, Suparna
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696681/
https://ncbi.nlm.nih.gov/pubmed/23673663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466748
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