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Modular Organization of α-Toxins from Scorpion Venom Mirrors Domain Structure of Their Targets, Sodium Channels

To gain success in the evolutionary “arms race,” venomous animals such as scorpions produce diverse neurotoxins selected to hit targets in the nervous system of prey. Scorpion α-toxins affect insect and/or mammalian voltage-gated sodium channels (Na(v)s) and thereby modify the excitability of muscle...

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Hlavní autoři: Chugunov, Anton O., Koromyslova, Anna D., Berkut, Antonina A., Peigneur, Steve, Tytgat, Jan, Polyansky, Anton A., Pentkovsky, Vladimir M., Vassilevski, Alexander A., Grishin, Eugene V., Efremov, Roman G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696675/
https://ncbi.nlm.nih.gov/pubmed/23637230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.431650
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