Cardiomyocyte ATP Production, Metabolic Flexibility, and Survival Require Calcium Flux through Cardiac Ryanodine Receptors in Vivo

Ca(2+) fluxes between adjacent organelles are thought to control many cellular processes, including metabolism and cell survival. In vitro evidence has been presented that constitutive Ca(2+) flux from intracellular stores into mitochondria is required for basal cellular metabolism, but these observ...

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Detalhes bibliográficos
Main Authors: Bround, Michael J., Wambolt, Rich, Luciani, Dan S., Kulpa, Jerzy E., Rodrigues, Brian, Brownsey, Roger W., Allard, Michael F., Johnson, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696672/
https://ncbi.nlm.nih.gov/pubmed/23678000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.427062
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