Bifunctional Lipocalin Ameliorates Murine Immune Complex-induced Acute Lung Injury

Molecules that simultaneously inhibit independent or co-dependent proinflammatory pathways may have advantages over conventional monotherapeutics. OmCI is a bifunctional protein derived from blood-feeding ticks that specifically prevents complement (C)-mediated C5 activation and also sequesters leuk...

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Detalhes bibliográficos
Main Authors: Roversi, Pietro, Ryffel, Bernhard, Togbe, Dieudonnée, Maillet, Isabelle, Teixeira, Mauro, Ahmat, Nurfilza, Paesen, Guido C., Lissina, Olga, Boland, Wilhelm, Ploss, Kerstin, Caesar, Joseph J. E., Leonhartsberger, Susanne, Lea, Susan M., Nunn, Miles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696655/
https://ncbi.nlm.nih.gov/pubmed/23625922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420331
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