Dynamic Ubiquitination of the Mitogen-activated Protein Kinase Kinase (MAPKK) Ste7 Determines Mitogen-activated Protein Kinase (MAPK) Specificity

Ubiquitination is a post-translational modification that tags proteins for proteasomal degradation. In addition, there is a growing appreciation that ubiquitination can influence protein activity and localization. Ste7 is a prototype MAPKK in yeast that participates in both the pheromone signaling a...

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Bibliographic Details
Main Authors: Hurst, Jillian H., Dohlman, Henrik G.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696639/
https://ncbi.nlm.nih.gov/pubmed/23645675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475707
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