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Microglial activation underlies cerebellar deficits produced by repeated cannabis exposure

Chronic cannabis exposure can lead to cerebellar dysfunction in humans, but the neurobiological mechanisms involved remain incompletely understood. Here, we found that in mice, subchronic administration of the psychoactive component of cannabis, delta9-tetrahydrocannabinol (THC), activated cerebella...

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Detalhes bibliográficos
Main Authors: Cutando, Laura, Busquets-Garcia, Arnau, Puighermanal, Emma, Gomis-González, Maria, Delgado-García, José María, Gruart, Agnès, Maldonado, Rafael, Ozaita, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696568/
https://ncbi.nlm.nih.gov/pubmed/23934130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67569
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