Depression and Anxiety Symptoms Among Women Who Carry the FMR1 Premutation: Impact of Raising a Child With Fragile X Syndrome Is Moderated by CRHR1 Polymorphisms

The fragile X mental retardation gene, FMR1, contains a polymorphic CGG repeat in the 5′-untranslated region of exon 1. Once unstable, this repeat is capable of expansion across generations. Women who carry a premutation allele (55–199 repeats) are at risk of passing on a full mutation allele (>2...

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Главные авторы: Hunter, Jessica Ezzell, Leslie, Mary, Novak, Gloria, Hamilton, Debra, Shubeck, Lisa, Charen, Krista, Abramowitz, Ann, Epstein, Michael P., Lori, Adriana, Binder, Elisabeth, Cubells, Joseph F., Sherman, Stephanie L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696495/
https://ncbi.nlm.nih.gov/pubmed/22573456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32061
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