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Deoxyribonucleic acid-mediated gene transfer in mammalian cells: molecular analysis of unstable transformants and their progression to stability.

To elucidate mechanisms involved in deoxyribonucleic acid-mediated gene transfer, we transferred the herpes simplex virus thymidine kinase gene (TK) into mouse Ltk- cells. Independent TK+ clones (transformants) and derivatives of each were tested for phenotypic expression and the presence and arrang...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Scangos, G A, Huttner, K M, Juricek, D K, Ruddle, F H
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1981
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6100961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.1.2.111-120.1981
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