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Droplet microfluidics for amplification-free genetic detection of single cells

In this article we present a novel droplet microfluidic chip enabling amplification-free detection of single pathogenic cells. The device streamlines multiple functionalities to carry out sample digitization, cell lysis, probe-target hybridization for subsequent fluorescent detection. A peptide nucl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rane, Tushar D., Zec, Helena, Puleo, Chris, Lee, Abraham P., Wang, Tza-Huei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696383/
https://ncbi.nlm.nih.gov/pubmed/22842841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2lc40537g
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