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Evolution of Type 2 Vaccine Derived Poliovirus Lineages. Evidence for Codon-Specific Positive Selection at Three Distinct Locations on Capsid Wall

Partial sequences of 110 type 2 poliovirus strains isolated from sewage in Slovakia in 2003–2005, and most probably originating from a single dose of oral poliovirus vaccine, were subjected to a detailed genetic analysis. Evolutionary patterns of these vaccine derived poliovirus strains (SVK-aVDPV2)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hovi, Tapani, Savolainen-Kopra, Carita, Smura, Teemu, Blomqvist, Soile, Al-Hello, Haider, Roivainen, Merja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696017/
https://ncbi.nlm.nih.gov/pubmed/23840537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066836
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