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Formation of heteroduplex DNA during mammalian intrachromosomal gene conversion.

We have studied intrachromosomal gene conversion in mouse Ltk- cells with a substrate designed to provide genetic evidence for heteroduplex DNA. Our recombination substrate consists of two defective chicken thymidine kinase genes arranged so as to favor the selection of gene conversion products. The...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Bollag, R J, Elwood, D R, Tobin, E D, Godwin, A R, Liskay, R M
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369596/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549110/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1546-1552.1992
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