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The Role of PTEN in Chronic Growth Hormone-Induced Hepatic Insulin Resistance

Chronic growth hormone (GH) therapy has been shown to cause insulin resistance, but the mechanism remains unknown. PTEN, a tumor suppressor gene, is a major negative regulator of insulin signaling. In this study, we explored the effect of chronic GH on insulin signaling in the context of PTEN functi...

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Detalhes bibliográficos
Main Authors: Gao, Yuan, Su, Peizhu, Wang, Chuqiong, Zhu, Kongqin, Chen, Xiaolan, Liu, Side, He, Jiman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695944/
https://ncbi.nlm.nih.gov/pubmed/23840818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068105
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