Enhanced Active Targeting via Cooperative Binding of Ligands on Liposomes to Target Receptors

To achieve effective active targeting in a drug delivery system, we previously developed dual-targeting (DT) liposomes decorated with both vascular endothelial growth factor receptor-1 (VEGFR-1)-targeted APRPG and CD13-targeted GNGRG peptide ligands for tumor neovessels, and observed the enhanced su...

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Detalhes bibliográficos
Main Authors: Sugiyama, Tomoki, Asai, Tomohiro, Nedachi, Yuki Murase, Katanasaka, Yasufumi, Shimizu, Kosuke, Maeda, Noriyuki, Oku, Naoto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695877/
https://ncbi.nlm.nih.gov/pubmed/23840738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067550
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