The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor.

Ítems similars

• Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells.
  per: Kavanaugh, W M, et al.
  Publicat: (1992)
• Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase.
  per: Yoakim, M, et al.
  Publicat: (1992)
• SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors.
  per: McGlade, C J, et al.
  Publicat: (1992)
• Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinase.
  per: Breeze, A L, et al.
  Publicat: (1996)
• The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity.
  per: Klippel, A, et al.
  Publicat: (1994)