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Drugs affecting microtubule dynamics increase alpha-tubulin mRNA accumulation via transcription in Tetrahymena thermophila.

In cultured mammalian cells, an increase in the amount of tubulin monomer due to treatment with a microtubule-depolymerizing agent results in a rapid decline in tubulin synthesis. This autoregulatory response is mediated through a posttranscriptional mechanism which decreases the stability of tubuli...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Stargell, L A, Heruth, D P, Gaertig, J, Gorovsky, M A
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369585/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1347905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1443-1450.1992
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