Novel microRNA-based assay demonstrates 92% agreement with diagnosis based on clinicopathologic and management data in a cohort of patients with carcinoma of unknown primary

BACKGROUND: Cancer of unknown or uncertain primary is a major diagnostic and clinical challenge, since identifying the tissue-of-origin of metastases is crucial for selecting optimal treatment. MicroRNAs are a family of non-coding, regulatory RNA molecules that are tissue-specific, with a great pote...

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Main Authors: Pentheroudakis, George, Pavlidis, Nicholas, Fountzilas, George, Krikelis, Dimitrios, Goussia, Anna, Stoyianni, Aikaterini, Sanden, Mats, St Cyr, Brianna, Yerushalmi, Noga, Benjamin, Hila, Meiri, Eti, Chajut, Ayelet, Rosenwald, Shai, Aharonov, Ranit, Spector, Yael
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695805/
https://ncbi.nlm.nih.gov/pubmed/23758919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-57
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