CK2-dependent phosphorylation of occludin regulates the interaction with ZO-proteins and tight junction integrity

BACKGROUND: Casein kinase 2 (CK2) is a ubiquitously expressed Ser/Thr kinase with multiple functions in the regulation of cell proliferation and transformation. In targeting adherens and tight junctions (TJs), CK2 modulates the strength and dynamics of epithelial cell-cell contacts. Occludin previou...

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Detalhes bibliográficos
Main Authors: Dörfel, Max J, Westphal, Julie K, Bellmann, Christian, Krug, Susanne M, Cording, Jimmi, Mittag, Sonnhild, Tauber, Rudolf, Fromm, Michael, Blasig, Ingolf E, Huber, Otmar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695765/
https://ncbi.nlm.nih.gov/pubmed/23758859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-40
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