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Novel Immunogenic HLA-A*0201-restricted Epidermal Growth Factor Receptor-specific T-cell Epitope in Head and Neck Cancer Patients

Therapeutic targeting of the epidermal growth factor receptor (EGFR), which is highly overexpressed and correlated with poor prognosis in colorectal and head and neck squamous cell carcinoma (SCCHN), has shown clinical efficacy using the blocking mAbs, cetuximab or panitumumab, but only in 10% to 20...

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מידע ביבליוגרפי
Main Authors: Andrade Filho, Pedro A., López-Albaitero, Andrés, Gooding, William, Ferris, Robert L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695408/
https://ncbi.nlm.nih.gov/pubmed/19952953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181b8f421
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