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Epstein-Barr Virus Nuclear Antigen 3C Regulates Cyclin A/p27 Complexes and Enhances Cyclin A-Dependent Kinase Activity

Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA3C) is essential for primary B-cell transformation. In this report we show that cyclin A, an activator of S phase progression, bound tightly to EBNA3C. EBNA3C interacted with cyclin A in vitro and associated with cyclin A complexes in EBV-transformed...

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Detalhes bibliográficos
Main Authors: Knight, Jason S., Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369513/
https://ncbi.nlm.nih.gov/pubmed/14747563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1981-1991.2004
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