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The Influenza B Virus Nonstructural NS1 Protein Is Essential for Efficient Viral Growth and Antagonizes Beta Interferon Induction

We analyzed the functions of the influenza B virus nonstructural NS1-B protein, both by utilizing a constructed mutant virus (ΔNS1-B) lacking the NS1 gene and by testing the activities of the protein when expressed in cells. The mutant virus replicated to intermediate levels in 6-day-old embryonated...

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Autores principales: Dauber, Bianca, Heins, Gudrun, Wolff, Thorsten
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC369500/
https://ncbi.nlm.nih.gov/pubmed/14747551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1865-1872.2004
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