The Influenza B Virus Nonstructural NS1 Protein Is Essential for Efficient Viral Growth and Antagonizes Beta Interferon Induction

We analyzed the functions of the influenza B virus nonstructural NS1-B protein, both by utilizing a constructed mutant virus (ΔNS1-B) lacking the NS1 gene and by testing the activities of the protein when expressed in cells. The mutant virus replicated to intermediate levels in 6-day-old embryonated...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Dauber, Bianca, Heins, Gudrun, Wolff, Thorsten
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Virus-Cell Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369500/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14747551/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.4.1865-1872.2004
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