Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II

We investigated blocking the TGF-β signaling pathway in HCC using two small molecule inhibitors (LY2157299, LY2109761) and a neutralizing humanized antibody (D10) against TGF-βRII. LY2157299 and LY2109761 inhibited HCC cell migration on Laminin-5, Fibronectin, Vitronectin, Fibrinogen and Collagen-I...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dituri, Francesco, Mazzocca, Antonio, Peidrò, Fernando Juan, Papappicco, Patrizia, Fabregat, Isabel, De Santis, Flavia, Paradiso, Angelo, Sabbà, Carlo, Giannelli, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694933/
https://ncbi.nlm.nih.gov/pubmed/23826206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados