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Tetanus Toxin Hc Fragment Induces the Formation of Ceramide Platforms and Protects Neuronal Cells against Oxidative Stress

Tetanus toxin (TeTx) is the protein, synthesized by the anaerobic bacteria Clostridium tetani, which causes tetanus disease. TeTx gains entry into target cells by means of its interaction with lipid rafts, which are membrane domains enriched in sphingomyelin and cholesterol. However, the exact mecha...

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Detalhes bibliográficos
Main Authors: Cubí, Roger, Candalija, Ana, Ortega, Arturo, Gil, Carles, Aguilera, José
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694913/
https://ncbi.nlm.nih.gov/pubmed/23826362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068055
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