Correction of Diabetic Hyperglycemia and Amelioration of Metabolic Anomalies by Minicircle DNA Mediated Glucose-Dependent Hepatic Insulin Production

Type 1 diabetes mellitus (T1DM) is caused by immune destruction of insulin-producing pancreatic β-cells. Commonly used insulin injection therapy does not provide a dynamic blood glucose control to prevent long-term systemic T1DM-associated damages. Donor shortage and the limited long-term success of...

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Main Authors: Alam, Tausif, Wai, Philip, Held, Dustie, Vakili, Sahar Taba Taba, Forsberg, Erik, Sollinger, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694888/
https://ncbi.nlm.nih.gov/pubmed/23826312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067515
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