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Innate Cellular Response to Virus Particle Entry Requires IRF3 but Not Virus Replication

Mammalian cells respond to virus infections by eliciting both innate and adaptive immune responses. One of the most effective innate antiviral responses is the production of alpha/beta interferon and the subsequent induction of interferon-stimulated genes (ISGs), whose products collectively limit vi...

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Autors principals: Collins, Susan E., Noyce, Ryan S., Mossman, Karen L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC369475/
https://ncbi.nlm.nih.gov/pubmed/14747536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1706-1717.2004
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