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Optimal Allocation of Sample Sizes to Multicenter Clinical Trials

In this article, we discussed an approach for optimal sample size allocation in designing multicenter clinical trials. The method we studied was adopted from a stratified sampling survey design. The sample size allocated to centers is a function of center's treatment cost, the standard deviatio...

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Detalhes bibliográficos
Main Authors: Lai, Dejian, Chang, Kuang-Chao, Rahbar, Mohammad H., Moye, Lemuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694743/
https://ncbi.nlm.nih.gov/pubmed/23786227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2013.789884
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