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Minimum curvilinearity to enhance topological prediction of protein interactions by network embedding

Motivation: Most functions within the cell emerge thanks to protein–protein interactions (PPIs), yet experimental determination of PPIs is both expensive and time-consuming. PPI networks present significant levels of noise and incompleteness. Predicting interactions using only PPI-network topology (...

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Detalhes bibliográficos
Main Authors: Cannistraci, Carlo Vittorio, Alanis-Lobato, Gregorio, Ravasi, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694668/
https://ncbi.nlm.nih.gov/pubmed/23812985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt208
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