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Up-regulation of alternate co-stimulatory molecules on proinflammatory CD28(null) T cells in bronchiolitis obliterans syndrome

Bronchiolitis obliterans syndrome (BOS) is associated with lack of immunosuppression of T cell proinflammatory cytokines and increased T cell granzyme B. Repeated antigen-driven proliferation down-regulates T cell CD28. We hypothesized that down-regulation of CD28 and up-regulation of alternate co-s...

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Detalhes bibliográficos
Main Authors: Hodge, G, Hodge, S, Ahern, J, Holmes-Liew, C-L, Reynolds, P N, Holmes, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694545/
https://ncbi.nlm.nih.gov/pubmed/23607447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12081
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