Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins.
The oncogene product of the avian sarcoma virus CT10, P47gag-crk, contains the SH2, SH2', and SH3 domains and binds proteins in a phosphotyrosine (ptyr)-dependent manner. In this study, we have determined the region of P47gag-crk essential for binding to ptyr-containing proteins. Mutant P47gag-crk p...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1991
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.3.1607-1613.1991 |
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