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Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins.

The oncogene product of the avian sarcoma virus CT10, P47gag-crk, contains the SH2, SH2', and SH3 domains and binds proteins in a phosphotyrosine (ptyr)-dependent manner. In this study, we have determined the region of P47gag-crk essential for binding to ptyr-containing proteins. Mutant P47gag-...

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Détails bibliographiques
Auteurs principaux: Matsuda, M, Mayer, B J, Hanafusa, H
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC369454/
https://ncbi.nlm.nih.gov/pubmed/1705010
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