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Intrinsic hyporesponsiveness of invariant natural killer T cells precedes the onset of lupus

Patients with systemic lupus erythematosus (SLE) display reduced numbers and functions of invariant natural killer T (iNK T) cells, which are restored upon treatment with corticosteroids and rituximab. It is unclear whether the iNK T cell insufficiency is a consequence of disease or is a primary abn...

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Detalhes bibliográficos
Main Authors: Yang, J-Q, Kim, P J, Halder, R C, Singh, R R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694531/
https://ncbi.nlm.nih.gov/pubmed/23607366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12079
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