A common polymorphic allele of the LH beta-subunit gene is associated with higher exogenous FSH consumption during controlled ovarian stimulation for assisted reproductive technology

BACKGROUND: V-betaLH is a common genetic variant of LH caused by two polymorphic base changes in the beta subunit gene, altering the amino acid sequence (Trp8Arg and Ile15Thr). In a previous-preliminary trial performed in women undergoing IVF, it was demonstrated that carriers of v-betaLH show sub-o...

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Main Authors: Alviggi, Carlo, Pettersson, Kim, Longobardi, Salvatore, Andersen, Claus Yding, Conforti, Alessandro, De Rosa, Pasquale, Clarizia, Roberto, Strina, Ida, Mollo, Antonio, De Placido, Giuseppe, Humaidan, Peter
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694457/
https://ncbi.nlm.nih.gov/pubmed/23725475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-11-51
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