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The Pro-inflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma

Chronic inflammation drives liver cancer pathogenesis, invasion and metastasis. Liver Kupffer cells (KC) have crucial roles in mediating the inflammatory processes that promote liver cancer but the mechanistic basis for their contributions are not fully understood. Here we show that expression of th...

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Detalhes bibliográficos
Main Authors: Wu, Juan, Li, Jiaqi, Salcedo, Rosalba, Mivechi, Nahid F., Trinchieri, Giorgio, Horuzsko, Anatolij
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694446/
https://ncbi.nlm.nih.gov/pubmed/22719066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0938
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