Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1–CXCR1/2-pathway

Experiments were designed to determine if the vasodilatory peptides maxadilan and pituitary adenylate cyclase-activating peptide (PACAP-38) may cause plasma leakage through activation of leukocytes and to what extent these effects could be due to PAC1 and CXCR1/2 receptor stimulation. Intravital mic...

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Main Authors: Svensjö, Erik, Saraiva, Elvira M., Amendola, Rafael Silveira, Barja-Fidalgo, Christina, Bozza, Marcelo T., Lerner, Ethan A., Teixeira, Mauro M., Scharfstein, Julio
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694432/
https://ncbi.nlm.nih.gov/pubmed/22036674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2011.10.003
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