Airway PI3K Pathway Activation Is an Early and Reversible Event in Lung Cancer Development

Although only a subset of smokers develop lung cancer, we cannot determine which smokers are at highest risk for cancer development, nor do we know the signaling pathways altered early in the process of tumorigenesis in these individuals. On the basis of the concept that cigarette smoke creates a mo...

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Main Authors: Gustafson, Adam M., Soldi, Raffaella, Anderlind, Christina, Scholand, Mary Beth, Qian, Jun, Zhang, Xiaohui, Cooper, Kendal, Walker, Darren, McWilliams, Annette, Liu, Gang, Szabo, Eva, Brody, Jerome, Massion, Pierre P., Lenburg, Marc E., Lam, Stephen, Bild, Andrea H., Spira, Avrum
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694402/
https://ncbi.nlm.nih.gov/pubmed/20375364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000251
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