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Dynein Light Chain 1 (DYNLT1) Interacts with Normal and Oncogenic Nucleoporins

The chimeric oncoprotein NUP98-HOXA9 results from the t(7;11)(p15;p15) chromosomal translocation and is associated with acute myeloid leukemia. It causes aberrant gene regulation and leukemic transformation through mechanisms that are not fully understood. NUP98-HOXA9 consists of an N-terminal porti...

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Hlavní autoři: Sarma, Nayan J., Yaseen, Nabeel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694108/
https://ncbi.nlm.nih.gov/pubmed/23840580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067032
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