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Neutrophils Turn Plasma Proteins into Weapons against HIV-1

As a consequence of innate immune activation granulocytes and macrophages produce hypochlorite/hypochlorous acid (HOCl) via secretion of myeloperoxidase (MPO) to the outside of the cells, where HOCl immediately reacts with proteins. Most proteins that become altered by this system do not belong to t...

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Detalhes bibliográficos
Main Authors: Speth, Cornelia, Brodde, Martin F., Hagleitner, Magdalena, Rambach, Günter, Van Aken, Hugo, Dierich, Manfred, Kehrel, Beate E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694086/
https://ncbi.nlm.nih.gov/pubmed/23840401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066073
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