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An Adaptor Molecule Afadin Regulates Lymphangiogenesis by Modulating RhoA Activity in the Developing Mouse Embryo

Afadin is an intracellular binding partner of nectins, cell-cell adhesion molecules, and plays important roles in the formation of cell-cell junctions. Afadin-knockout mice show early embryonic lethality, therefore little is known about the function of afadin during organ development. In this study,...

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Detalhes bibliográficos
Main Authors: Majima, Takashi, Takeuchi, Keisuke, Sano, Keigo, Hirashima, Masanori, Zankov, Dimitar P., Tanaka-Okamoto, Miki, Ishizaki, Hiroyoshi, Miyoshi, Jun, Ogita, Hisakazu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694064/
https://ncbi.nlm.nih.gov/pubmed/23840823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068134
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