Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration

Age is the most significant risk factor for atherosclerosis; however, the link between age and atherosclerosis is poorly understood. During both aging and atherosclerosis progression, the blood vessel wall stiffens owing to alterations in the extracellular matrix. Using in vitro and ex vivo models o...

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Main Authors: Huynh, John, Nishimura, Nozomi, Rana, Kuldeepsinh, Peloquin, John M., Califano, Joseph P., Montague, Christine R., King, Michael R., Schaffer, Chris B., Reinhart-King, Cynthia A.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693751/
https://ncbi.nlm.nih.gov/pubmed/22158860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002761
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