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Engineering the type III secretion system in non-replicating bacterial minicells for antigen delivery
Type III protein secretion systems are being considered for vaccine development since virtually any protein antigen can be engineered for delivery by these nanomachines into the class I antigen presentation pathway to stimulate antigen-specific CD8(+) T cells (12). A limitation in the use of this sy...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3693737/ https://ncbi.nlm.nih.gov/pubmed/23481398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2594 |
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