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Insulin Signaling: Inositol Phosphates Get Into the Akt
An acute but transient response to insulin is essential for glucose homeostasis in mammals. Chakraborty et al. (2010) uncover a new feedback mechanism regulating insulin signaling. They show that the inositol pyrophosphate IP7, which is produced in response to insulin, inhibits the Akt kinase, a pri...
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| Formato: | Artigo |
| Idioma: | Inglês |
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2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3693466/ https://ncbi.nlm.nih.gov/pubmed/21145450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.11.040 |
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