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Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens

There is accumulating evidence that the nucleus accumbens (NAc) has an important role in the pathophysiology of depression. As the NAc is a key component in the neural circuitry of reward, it has been hypothesized that anhedonia, a core symptom of depression, might be related to dysfunction of this...

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Detalhes bibliográficos
Main Authors: Bessa, J M, Morais, M, Marques, F, Pinto, L, Palha, J A, Almeida, O F X, Sousa, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693402/
https://ncbi.nlm.nih.gov/pubmed/23736119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2013.39
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