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Hypoxia and Cytoplasmic Alkalinization Upregulate Growth Hormone Expression in Lymphocytes

We report here that culture of lymphoid cells under hypoxic conditions showed an increase in both luciferase expression from a GH-promoter luciferase construct and the levels of lymphocyte GH. The effect was mimicked by treatment of cells with cobalt chloride consistent with a specific oxygen-sensin...

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Detalhes bibliográficos
Autor principal: Weigent, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693391/
https://ncbi.nlm.nih.gov/pubmed/23639351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2013.03.007
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