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Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis.

We have examined the effects of protein synthesis inhibition on histone gene expression during the HeLa cell cycle. Histone mRNAs, which normally are rapidly degraded in the absence of DNA synthesis, persist and increase in concentration when translation is inhibited before DNA replication is halted...

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Detalhes bibliográficos
Main Authors: Sive, H L, Heintz, N, Roeder, R G
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369282/
https://ncbi.nlm.nih.gov/pubmed/6441888
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