Cholera toxin treatment stimulates tumorigenicity of Rous sarcoma virus-transformed cells.

Chinese hamster ovary cells transformed by Rous sarcoma virus form tumors poorly in nude mice. Tumorigenicity was markedly stimulated by pretreatment of the cells with cholera toxin, which raises cyclic AMP levels and activates cyclic AMP-dependent protein kinase. Increased tumorigenicity was manife...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gottesman, M M, Roth, C, Vlahakis, G, Pastan, I
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC369272/
https://ncbi.nlm.nih.gov/pubmed/6098816
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