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Plasmodium falciparum Erythrocytic Stage Parasites Require the Putative Autophagy Protein PfAtg7 for Normal Growth

Analysis of the Plasmodium falciparum genome reveals a limited number of putative autophagy genes, specifically the four genes involved in ATG8 lipidation, an essential step in formation of autophagosomes. In yeast, Atg8 lipidation requires the E1-type ligase Atg7, an E2-type ligase Atg3, and a cyst...

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Bibliografische gegevens
Hoofdauteurs: Walker, Dawn M., Mahfooz, Najmus, Kemme, Katherine A., Patel, Viral C., Spangler, Maribeth, Drew, Mark E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692556/
https://ncbi.nlm.nih.gov/pubmed/23825614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067047
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