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MicroRNA Profiling of Salivary Adenoid Cystic Carcinoma: Association of miR-17-92 Upregulation with Poor Outcome

BACKGROUND: Salivary adenoid cystic carcinoma (ACC) is a rare relentlessly progressive malignant tumor. The molecular events associated with ACC tumorigenesis are poorly understood. Variable microRNAs (miRNA) have been correlated with tumorigenesis of several solid tumors but not in ACC. To investig...

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Main Authors: Mitani, Yoshitsugu, Roberts, Dianna B., Fatani, Hanadi, Weber, Randal S., Kies, Merrill S., Lippman, Scott M., El-Naggar, Adel K.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692530/
https://ncbi.nlm.nih.gov/pubmed/23825564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066778
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