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Tissue-Specific 5′ Heterogeneity of PPARα Transcripts and Their Differential Regulation by Leptin

The genes encoding nuclear receptors comprise multiple 5′untranslated exons, which give rise to several transcripts encoding the same protein, allowing tissue-specific regulation of expression. Both human and mouse peroxisome proliferator activated receptor (PPAR) α genes have multiple promoters, al...

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Autori principali: Garratt, Emma S., Vickers, Mark H., Gluckman, Peter D., Hanson, Mark A., Burdge, Graham C., Lillycrop, Karen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692471/
https://ncbi.nlm.nih.gov/pubmed/23825665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067483
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