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Tissue-Specific 5′ Heterogeneity of PPARα Transcripts and Their Differential Regulation by Leptin

The genes encoding nuclear receptors comprise multiple 5′untranslated exons, which give rise to several transcripts encoding the same protein, allowing tissue-specific regulation of expression. Both human and mouse peroxisome proliferator activated receptor (PPAR) α genes have multiple promoters, al...

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Detalhes bibliográficos
Main Authors: Garratt, Emma S., Vickers, Mark H., Gluckman, Peter D., Hanson, Mark A., Burdge, Graham C., Lillycrop, Karen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692471/
https://ncbi.nlm.nih.gov/pubmed/23825665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067483
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