Underwhelming the Immune Response: Effect of Slow Virus Growth on CD8(+)-T-Lymphocyte Responses

The speed of virus replication has typically been seen as an advantage for a virus in overcoming the ability of the immune system to control its population growth. Under some circumstances, the converse may also be true: more slowly replicating viruses may evoke weaker cellular immune responses and...

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Main Authors: Bocharov, Gennady, Ludewig, Burkhard, Bertoletti, Antonio, Klenerman, Paul, Junt, Tobias, Krebs, Philippe, Luzyanina, Tatyana, Fraser, Cristophe, Anderson, Roy M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC369240/
https://ncbi.nlm.nih.gov/pubmed/14963121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.5.2247-2254.2004
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