Binding of the 2F5 Monoclonal Antibody to Native and Fusion-Intermediate Forms of Human Immunodeficiency Virus Type 1 gp41: Implications for Fusion-Inducing Conformational Changes

We investigated how the broadly neutralizing monoclonal antibody 2F5 affects the human immunodeficiency virus type 1 envelope glycoprotein as it undergoes receptor-induced conformational changes and show that 2F5 binds both native and fusion-intermediate conformations, suggesting inhibition of a lat...

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में प्रकाशित:	J Virol
मुख्य लेखकों:	de Rosny, Eve, Vassell, Russell, Jiang, Shibo, Kunert, Renate, Weiss, Carol D.
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology (ASM) 2004
विषय:	Vaccines and Antiviral Agents
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369236/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14963170/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.5.2627-2631.2004
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