Novel phytochemical–antibiotic conjugates as multitarget inhibitors of Pseudomononas aeruginosa GyrB/ParE and DHFR

BACKGROUND: There is a dearth of treatment options for community-acquired and nosocomial Pseudomonas infections due to several rapidly emerging multidrug resistant phenotypes, which show resistance even to combination therapy. As an alternative, developing selective promiscuous hybrid compounds for...

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Bibliografiska uppgifter
Huvudupphovsmän: Jayaraman, Premkumar, Sakharkar, Kishore R, Lim, ChuSing, Siddiqi, Mohammad Imran, Dhillon, Sarinder K, Sakharkar, Meena K
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2013
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692347/
https://ncbi.nlm.nih.gov/pubmed/23818757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S43964
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